Hu Zhang / Japanese Knotweed (Polygonum Cuspidatum)
Bambou Japonais, Bambou Mexicain, Extrait de Hu Zhang, Fallopia japonica, Fleece Flower, Giant Knotweed, He Shou Wu, Hu Zhang Extract, Hu Zhang Root, Itadori, Japanese Bamboo, Japanese Knotweed, Japanese Knotwood, Mexican Bamboo, PCWE, Persicaire Cuspidée, Polygoni Multiflora, Polygonum cuspidatum, Racine de Hu Zhang, Renouée à Feuilles Pointues, Renouée du Japon, Renouée Japonaise, Reynoutria japonica, Tiger Cane.
Hu zhang is the Chinese name given to a plant with the scientific name of Polygonum cuspidatum. North American varieties are often referred to as “Mexican bamboo.” The root is used as medicine.
Hu zhang is used for conditions of the heart and blood vessels including “hardening of the arteries” (atherosclerosis), high cholesterol, and heart disease; and for digestion problems including constipation, liver disease (hepatitis), and gallstones. It is also used for cancer, skin burns, pain and swelling of the bone (osteomyelitis) and gout.
Women sometimes use hu zhang for painful menstrual periods and menopausal symptoms such as hot flashes.
There is not enough known about how hu zhang might work. Some chemicals in hu zhang might decrease how fast some cells grow.
Insufficient Evidence for:
More evidence is needed to rate the effectiveness of hu zhang for these uses.
There is not enough known about hu zhang to know if it is safe.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Not enough is known about the use of hu zhang during pregnancy and breast-feeding. Stay on the safe side and avoid use.
Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: There is some developing evidence that hu zhang might act like estrogen. If you have any condition that might be made worse by exposure to estrogen, don’t use hu zhang until more is known.
Moderate Interaction. Be cautious with this combination:
Estrogens interacts with HU ZHANG
Hu zhang seems to have some of the same effects as estrogen. Taking hu zhang along with estrogens might decrease the effects of estrogens.
Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with HU ZHANG
Some medications are changed and broken down by the liver.
Hu zhang contains a chemical called resveratrol. Resveratrol might decrease how quickly the liver breaks down some medications. Taking hu zhang along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking hu zhang, talk to your healthcare provider if you are taking any medications that are changed by the liver.
Some medications changed by the liver include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and many others.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with HU ZHANG
Hu zhang contains a chemical called resveratrol. Resveratrol might slow blood clotting. Taking hu zhang along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.